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River Cruise Tours with Vacations By Rail

There is no better way to see the best of Europe's historic cities and charming riverside towns than by rail and river cruise. 

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Order one of our free brochures featuring a collection of our most popular rail itineraries to destinations around the globe.

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AMADEUS Queen Sailing

Experience Our Most Popular Rail & Cruise Tours

River CruiseRiver Cruise
Jungfrau Express
Save up to $500
Top of Europe & The Majestic Rhine Cruise
4.3 stars(16 reviews)
Escorted
2026MayJunJul
10 days from
$3,895 pp $3,495 pp
View Details
River CruiseRiver Cruise
Save up to $500
 Munich, Bavaria & the Classic Danube
Escorted
2026JunJulAug
11 days from
$3,295 pp $2,995 pp
View Details
River CruiseRiver Cruise
Keukenof Gardens
Save up to $500
Springtime Tulips & Keukenhof Gardens
4.3 stars(19 reviews)
Escorted
2026Apr
8 days from
$2,395 pp $2,195 pp
View Details
River CruiseRiver Cruise
Glacier Express
Save up to $500
Glacier Express & the Majestic Rhine
4.4 stars(42 reviews)
Escorted
2026MayJunJul
11 days from
$4,395 pp $3,995 pp
View Details
River CruiseRiver Cruise
Basel
Save up to $500
The Romantic Rhine: Amsterdam to Basel
Escorted
2026MayJunJul
8 days from
$2,395 pp $2,195 pp
View Details
River CruiseRiver Cruise
Save up to $500
Lisbon & Premium Golden Douro
Escorted
2026MayJunOct
11 days from
$4,395 pp $3,995 pp
View Details
River CruiseRiver Cruise
Eiffel Tower on the Rhone
Paris, Provence & the Elegant Rhône
Escorted
2026AprJunJulAugSep
11 days from
$4,195 pp $3,795 pp
View Details
River CruiseRiver Cruise
Salzburg
Save up to $500
The Classic Blue Danube Cruise
4.7 stars(15 reviews)
Escorted
2026JunJulAug
8 days from
$1,995 pp $1,795 pp
View Details

Why Choose Vacations by Rail?

For more than 20 years, we have been the trusted experts on rail travel, from the United States and Canada to all round the world.

Why choose Vacations by Rail:

  • Discover thoughtfully planned independent and escorted itineraries.
  • Count on our dedicated rail specialists to guide you through questions and bookings.
  • Choose from the biggest selection of rail vacations and cruises.
  • Benefit from our 20 years of experience in the travel industry.
  • Receive an exclusive flight quote to pair with your vacation.
A World of Possibilities

Vacations By Rail offers an unrivaled collection of rail tours to top destinations around the globe - But did you know we also offer five-star river cruise tours as well? If you're looking for inspiration for your river cruise vacation, consider these popular rivers and countries.

See more about what the experience is like on this page.

Danube
Danube CruisesView tours
Germany River CruisesView tours
Rhine
Rhine CruisesView tours
Switzerland River CruisesView tours
Seine
Seine CruisesView tours
France River CruisesView tours